

The Zebra ZD621t-HC is the healthcare version of Zebra's premium 4-inch ZD621 desktop printer – the successor to the ZD620-HC, made for prescription, lab and specimen, blood and IV bag and patient record labels as well as patient ID wristbands. As a thermal transfer model with a dual-capacity ribbon holder it takes both 74 m and 300 m ribbons for durable, smudge-proof labels on paper and synthetic materials. It prints sharp 300 dpi labels up to 108 mm wide at up to 152 mm/s (6 ips), and the standard 4.3-inch colour touch display guides staff through setup, media loading and calibration. White, disinfectant-ready and UV-resistant plastics with a sealed button interface withstand constant cleaning, and the IEC 60601-1 certified power supply is approved for use in healthcare facilities. This version, ZD6AH43-30ER02EZ, adds the latest Wi-Fi 6 (802.11ax) + Bluetooth 5.3 radio to USB, USB Host, Ethernet and RS-232 serial for fast, secure wireless network and mobile printing; the power supply, EU and UK power cords and a USB cable are included, so it is ready to print as soon as you add labels and a ribbon.
📦 What's in the box – ZD6AH43-30ER02EZ
- ✅ Zebra ZD621t-HC printer – White, colour touch display, USB, USB Host, Ethernet, RS-232, Wi-Fi 6 + Bluetooth 5.3
- ✅ Power supply – IEC 60601-1 certified healthcare power supply, 100–240 V
- ✅ Power cords – EU (Schuko) and UK (type G) plugs – use the one for your country
- ✅ USB cable – USB A to B, for connecting to your PC
- ✅ Empty ribbon take-up cores – for 74 m (12.7 mm core) and 300 m (25.4 mm core) ribbons
- ✅ Ribbon core adapters (2) – for using non-Zebra 300 m ribbons
- ✅ Setup guide – drivers, ZebraDesigner Essentials and manuals are a free download from Zebra
- ❌ Labels – NOT included
- ❌ Thermal transfer ribbon – NOT included
✅ Ready to print out of the box – power supply, power cords and USB cable are included; you only need labels and a ribbon.
💡 Useful extras: a field-installable cutter or label dispenser (Zebra P1112640-232 or Zebra P1112640-233); the battery base with battery for cart-based printing (Zebra P1080383-600 + Zebra P1080383-603); the Zebra P1112640-054 adapter kit for 38, 51 and 76 mm label cores; Zebra 105950-035 cleaning pens for the printhead.
Key Features
- Built for healthcare – white, disinfectant-ready plastics withstand frequent cleaning, the UV-resistant housing supports UV disinfection and the sealed buttons keep liquids out; the power supply is IEC 60601-1 certified.
- Dual-capacity ribbon holder – use economical 300 m Zebra ribbons (1:4 ribbon-to-media ratio) or compact 74 m ribbons; adapters for non-Zebra 300 m ribbons are included.
- 300 dpi (12 dots/mm) – crisp small text, 2D codes and tiny labels at up to 152 mm/s (6 ips)
- 4.3-inch colour touch display as standard – step-by-step setup wizards, media-loading and calibration guidance and troubleshooting animations, plus five status icons that show the printer state at a glance.
- Handles virtually any media – roll-fed or fanfold labels, tags and continuous receipt paper, plus patient wristbands from 15 mm to 118 mm wide, with a movable black-mark sensor and a multi-position gap sensor.
- Wi-Fi 6 + Bluetooth 5.3 – factory-installed 802.11ax radio for fast, stable wireless printing on busy hospital networks and Bluetooth for mobile devices, on top of Ethernet, serial, USB and USB Host.
- Fits into your existing fleet – supports ZPL II and EPL 2, emulates other printer languages with Print DNA Virtual Devices and runs your existing GK-series label formats unchanged.
- Secure and remotely manageable – Print DNA with PrintSecure and Printer Profile Manager Enterprise; 512 MB flash, 256 MB SDRAM, real-time clock and ENERGY STAR certification.
- Upgrade on site – field-installable cutter or label dispenser (peeler), an attached battery base with 2750 mAh battery and carrying case for printing at the bedside or on carts, and the ZKDU keyboard display for stand-alone use.
Ideal Applications
- Pharmacy – prescription and medication labels
- Laboratory – lab and specimen labels for sample tubes and containers
- Patient identification – patient ID wristbands and patient record labels
- Blood bank and wards – blood and IV bag labels
- Hospital administration and sterile services – asset, file and instrument tray labels
All ZD621-HC Versions
The highlighted row is the version you are currently viewing.
| Part Number | Print Method | Resolution | Wireless | |
|---|---|---|---|---|
| ZD6AH42-D0EF00EZ | Direct thermal | 203 dpi | BLE (setup only) | View product |
| ZD6AH42-D0EL02EZ | Direct thermal | 203 dpi | Wi-Fi 5 + BT 4.1 | View product |
| ZD6AH43-D0EF00EZ | Direct thermal | 300 dpi | BLE (setup only) | View product |
| ZD6AH42-30EF00EZ | Thermal transfer | 203 dpi | BLE (setup only) | View product |
| ZD6AH43-30EF00EZ | Thermal transfer | 300 dpi | BLE (setup only) | View product |
| ZD6AH43-30EL02EZ | Thermal transfer | 300 dpi | Wi-Fi 5 + BT 4.1 | View product |
| ZD6AH43-30ER02EZ (this version) | Thermal transfer | 300 dpi | Wi-Fi 6 + BT 5.3 | Viewing |
Technical Specifications
| Part Number | ZD6AH43-30ER02EZ |
|---|---|
| Model | Zebra ZD621t-HC (ZD621-HC healthcare series) |
| Printer Type | 4-inch premium healthcare desktop label printer (ZD600 Series) – thermal transfer, 74 m / 300 m ribbon roll |
| Print Method | Thermal transfer and direct thermal |
| Resolution | 300 dpi (12 dots/mm) |
| Print Speed | Up to 152 mm/s (6 in/s) |
| Max Print Width | 108 mm (4.27 in) |
| Media Width | 15–118 mm (0.585–4.65 in) |
| Label Length | 6.4–991 mm (0.25–39 in) |
| Roll Diameter | Max. 127 mm (5.0 in) outer diameter |
| Core Size | 12.7 mm (0.5 in) and 25.4 mm (1 in) standard; 38.1, 50.8 and 76.2 mm with optional adapters |
| Media Thickness | 0.08–0.19 mm (max. in tear-off mode) |
| Media Type | Roll-fed or fanfold; die-cut or continuous labels with or without black mark, tag stock, continuous receipt paper, wristbands |
| Sensors | Full-width movable reflective / black-mark sensor; multi-position transmissive / gap sensor |
| Ribbon | Zebra 300 m (25.4 mm core, OD 66 mm, 1:4 ribbon-to-media) or 74 m (12.7 mm core, OD 34 mm, 1:1); width 33.8–109.2 mm; ink side out; adapters for non-Zebra 300 m ribbons included; media dancer |
| Interfaces | USB 2.0, USB Host, Ethernet 10/100 and RS-232 serial – all standard |
| Wireless | Wi-Fi 6 (802.11ax) + Bluetooth 5.3, factory-installed; BLE for setup |
| NFC | Print Touch (NFC) tag – tap to pair and open Zebra help pages |
| Memory | 512 MB Flash, 256 MB SDRAM (64 MB Flash / 8 MB SDRAM user available); real-time clock |
| Printer Languages | ZPL II, EPL 2, XML, ZBI, PDF Direct; Link-OS |
| Fonts / Character Sets | 16 resident expandable ZPL II bitmap fonts, 2 scalable ZPL fonts, 5 EPL2 fonts, native OpenType support, Unicode |
| Barcodes | 1D: Code 11, Code 39, Code 93, Code 128, ISBT-128, UPC-A/E, EAN-8/13 (+2/+5), Plessey, Postnet, 2-of-5 variants, Logmars, MSI, Codabar, Planet; 2D: Codablock, PDF417, Code 49, Data Matrix, MaxiCode, QR Code, MicroPDF, Aztec |
| Display | 4.3-inch full-colour LCD touch display (480 × 272) with 3-button interface; 5 status icons |
| Media Options | Tear-off (standard); field-installable dispenser / peeler with label-present sensor (P1112640-233) and cutter (P1112640-232) |
| Options | Attached battery base + 2750 mAh battery, carrying case, ZKDU keyboard display unit, media core adapters, mounting plate |
| Drivers & Software | Print DNA (PrintSecure, Printer Profile Manager Enterprise, Zebra Printer Setup app), ZebraDesigner Essentials (free), Windows drivers |
| Mobile Printing | Android, iOS, Windows |
| Power Supply | Auto-detecting 100–240 V AC, 50–60 Hz (PFC), IEC 60601-1 certified healthcare power supply; ENERGY STAR, Efficiency Level VI; optional 2750 mAh battery |
| Healthcare Features | White healthcare colour scheme; disinfectant-ready, easy-to-clean plastics; sealed button interface; UV-resistant housing |
| Dimensions (W × D × H) | 202 × 267 × 192 mm |
| Weight | 2.5 kg |
| Color | White |
| Operating Temperature | 4.4 °C to 41 °C |
| Storage Temperature | −40 °C to 60 °C |
| Humidity | 10–90% non-condensing (storage 5–95%) |
| Certifications | IEC 62368-1, EN 55032 Class B, EN 55035, EN 61000-3-2/-3-3, EN 300 328, EN 301 893, CE, ENERGY STAR, RoHS; power supply IEC 60601-1 |
| Warranty | 24 months (Zebra standard warranty) |
| In the Box | Zebra ZD621t-HC printer (white healthcare housing, 4.3-inch colour touch display; USB, USB Host, Ethernet, RS-232, Wi-Fi 6 + Bluetooth 5.3), IEC 60601-1 certified healthcare power supply, power cords EU + UK, USB cable, empty ribbon take-up cores (12.7 mm + 25.4 mm), 2 ribbon core adapters for non-Zebra 300 m ribbons, quick start guide, regulatory guide – labels and ribbon NOT included |
Which ZD621-HC should you choose? The ZD621d-HC (direct thermal) needs no ribbon and suits patient wristbands, specimen and short-life labels; the ZD621t-HC uses 74 m or 300 m ribbon rolls for durable labels on paper and synthetic media – for example lab labels that must survive freezers and solvents. 203 dpi suits most barcodes and labels, while 300 dpi gives crisper small text and tiny 2D codes on specimen tubes. Every version has Ethernet and serial; choose Wi-Fi 5 or Wi-Fi 6 to print wirelessly on the hospital network. Compare other models in our Desktop Label Printers collection or contact our team for volume pricing.
Recently Viewed
Don't forget! The products that you viewed. Add it to cart now.
People Also Bought
Here’s some of our most similar products people are buying. Click to discover trending style.































































